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419
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Learning Objectives:
Immunity Rules
Reading Assignment:
Janeway et al. Chapter 1 or Parham
Chapter 1
Supplementary Materials: Infectious Disease, Antigen, Immunity Rules, ToolBox
Immunity Rules is
an overview of immunology: the functions of the immune system, the physical organization
of the immune system, and a bird's eye look at what you will be learning in more
detail in MIC 419. It is heavy on vocabulary. Immunology has its own jargon,
and by the end of the course you'll be able to speak immunology as well as understand
and use the basic concepts.
When you finish Immunity Rules,
you should be able to
- Describe the four basic types of
pathogens and the steps in pathogenesis, with an example of how each step is
accomplished (Review Infectious
Disease if necessary).
- Describe the functions of the immune
system.
- Define
immunity, and give examples of how it can be acquired actively and passively.
- Describe the physical immune system,
including mucosal and skin barriers, organs, cells, and circulation. List one
function for each cell type.
- Describe the general principles
of immune recognition. Include in your description the definitions of antigen
and discuss the similarities and differences between antigen receptors of the
innate and adaptive immune systems.
- Describe the differences in B cell
and T cell antigen recognition.
- Follow the life of a lymphoid progenitor
as it becomes a B cell and then responds to antigen. Discuss the location of
the cell at each stage and what must occur for it to progress to a plasma cell.
Repeat the process for a T cell and discuss the functions of the three types
of effector T cells.
- List the three ways in which antibodies
help to eliminate pathogen.
- Define immune memory and list
two ways in which it might be detected.
- Give one example each of an immune
deficiency and an immune hypersensitivity.
- Apply this information to a clinical
case - be able to predict which parts of the immune system will respond to a
bacterial or viral pathogen.
Practice Quiz: Immunity Rules Tutorial
http://microvet.arizona.edu/Courses/MIC419/LOImmunityRules.html
Written by Janet M. Decker, PhD jdecker@u.arizona.edu
Last modified
January 10, 2006
