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Normal Human Immune System Parameters

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Normal   Values   for   Human   Serum  Proteins
Serum IgA
60-380 mg/dl
Serum IgE
0-200 IU*/ml
Serum IgG
(60-70% IgG1, 14-20% IgG2,
4-8% IgG3, 2-6% IgG4)
600-1400 mg/dl
Serum IgM
40-345 mg/dl
Complement C3
111-171 mg/dl
Albumin
3.5-5 gm/dl

*1   IU = 2.4 ng/protein

Normal   Values   for   Human  Leukocytes
 
B cells
T cells
Phagocytes
Normal numbers
per ml of blood
Total leukocytes =4,300-10,800
300
Total
1,000-2,500
CD4
500-1,600
CD8
300-900
Monocytes
165-600
Neutrophils
3,000-5,500
Eosinophils
50-250
Basophils
20
Measurement of
function in vivo
Serum Ig levels
Specific antibody levels
Skin test
___
Measurement of
function in vitro
Antibody production in response to PWM mitogen
T cell proliferation in response to PHA or TT
Phagocytosis
NBT uptake
Intacellular killing of bacteria

NBT = nitro blue tetrazolium; PHA = phytohemagglutinin; PWM = pokeweed mitogen; TT = tetanus toxoid.

Adapted from Janeway, C. A., P. Travers, M. Walport, M. Schlomchik. Immunobiology (5th edition), Garland Publishing, New York, 2001.

For details of tests, see ToolBox.

See also

Blood Cells http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/B/Blood.html

Blood Cell Photomicrographs http://www.unomaha.edu/~swick/blood.html

CD Antigens Used for Hematopathology http://depts.washington.edu/labweb/dept/div/heme/cds.html

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http://microvet.arizona.edu/Courses/MIC419/ToolBox/normalvalues.html
Written by Janet M. Decker, PhD      jdecker@u.arizona.edu
Last modified March 24, 2006