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Learning Objectives:
Immunity Rules
Reading Assignment: Chapter
1, The Immune System by Parham
Supplementary Materials:
Infectious Disease, Immunity
Rules,
Antigen, ToolBox
Immunity Rules is
an overview of immunology: the function of the immune system, the physical organization
of the immune system, and a bird's eye look at what you will be learning in more
detail in MIC 419. It is heavy on vocabulary. Immunology has its own jargon,
and by the end of the course you'll be able to speak immunology as well as understand
and use the basic concepts.
The Learning Objectives pages
list the key concepts you should know from each section of the course. You are
also expected to be familiar with the terms bolded in the text. In addition to
The Immune System by Parham, study aids include online Tutorials with study questions
and a ToolBox containing a Glossary, Reading and Writing About Immunology, and
information about immunological techniques.
When you finish Immunity Rules,
you should be able to
- Describe the function of the immune
system. Review Infectious
Disease, and be able to describe the four basic types of pathogens and the
steps in pathogenesis, with an example of how each step is accomplished.
- Define
immunity, and give examples of how it can be acquired actively and passively.
- Describe the physical immune system,
including mucosa, organs, cells, and circulation. List one function for each
cell type.
- Summarize the process of innate
immunity. Include in your description the cells that are involved and their
functions as well as the roles of cytokines, mannose-binding protein, and complement
in inflammation.
- Describe the general principles
of immune recognition. Include in your description the definitions of antigen
and discuss the similarities and differences between antigen receptors of the
innate and adaptive immune systems.
- Describe the differences in B cell
and T cell antigen recognition.
- Follow the life of a lymphoid progenitor
as it becomes a B cell and then responds to antigen. Discuss the location of
the cell at each stage and what must occur for it to progress to a plasma cell.
Repeat the process for a T cell and discuss the functions of the three types
of effector T cells.
- List the three ways in which antibodies
help to eliminate pathogen.
- Describe immune memory and list
two ways in which it might be detected.
- Give one example each of an immune
deficiency and an immune hypersensitivity.
- Apply this information to a clinical
case - be able to predict which parts of the immune system will respond to a
bacterial or viral pathogen.
http://microvet.arizona.edu/Courses/MIC419web/LOImmunityRules.html
Written by Janet M. Decker, PhD jdecker@u.arizona.edu
Last modified
June 9, 2003
