Topics
and Outlines (NOTE!
* = Required
reading)
Note: The lecture outlines and required readings will be available for
purchase as CLASS NOTES at the UA Bookstore
Each topic outline below can be used
to follow along with the lecture. The outlines contain the topics, mostly in
order, that are covered in class. In addition, each outline has study questions
and a case history for review.You should be able to answer these questions and
fully understand the case history. The questions and some of the cases will
not be specifically covered in class, but you can bring up the questions in
class if you wish. Available here are the case histories
from all the outlines, all of the questions
from the outlines, and brief answers. In
addition, you may find the study guide questions,
drawn from previous exams, very useful.
You are expected to read the 1-2 items with an "*"
before the lecture, either from the on-line version or the printed version,
available as a class packet at the bookstore. Other items listed below are optional
(and not included in the printed packet) and interesting. If you are curious
about the virus that is presented in class you can learn more about that group
of viruses by clicking on the virus family name. The exam questions will be
derived from the lecture and required reading only.
March 30
*
= Required reading
Topic 1 Outline: Emergence,
then Disappearance? SARS (2002-3) and Nipah virus (1998-1999)
Optional
introductory paper: "From Pasteur
to Genomics: Challenges in Infectious Disease" Fig1
Fig2
Quote from lecture
about early SARS
*CDC
Informationon SARS *Severe
Acute Respiratory Syndrome - an emergent Coronavirus
Want to learn about Coronaviridae
? SARS-virus picture
*CDC
Summary of Nipah and Hendra *Deadly
Nipah virus - an emergent Paramyxovirus
Want to learn about Paramyxoviridae
?
SARS in China SARS
China Peak of cases Guangdong
Province Travel
China Guide Com
SARS in Vietnam and Canada
Nipah virus geography -
CDC investigation of Bats in Malaysia Malysia
April 4
Topic 2 Outline:
Foot
and Mouth: Fast-Moving-Disease
*The
Foot and Mouth Epidemic In Great Britain (PDF)
or (HTML) BBC
News Page 21 Feb 2001
Great Britain FMD SiteDepartment
of Environment, Food and Rural Affairs, Foot and Mouth Information
Want to learn more about Picorna
Tree ? Picornaviridae
? FMD
in Europe, 2001
April 6
Topic 3 Outline: Rabies,
Geography, Raccoons, Vampire Bats, and War
*The CDC comprehensive site on rabies with many sub
sections - Review:
Natural History Epidemiology
*The emergence of
Racoon Rabies in Eastern USA Epizootic
Diagram Texas
Vaccine Diagram
A brief summary
of rabies facts and myths
Animal Rabies Cases in Arizona: 2004 2005
Texas
Oral Rabies Vaccine Program ORVP
Impact
More about Rhabdoviridae
? Rabies
Emergency 2005 in Tucson
Rabies
Emergency 2006 in Tucson
Graduate
Section Papers: Molecular
Epi of Rabies in California Molecular
Epi of Lyssavirus in Australia
April 11
Topic 4 Outline:
Viruses and Vectors: From the Panama Canal, the Nile,
and Old Tires.
*Resurgence
of vector-borne diseaes (See brief parts of article dealing with Arboviruses)
*Emergence
of Dengue (Nice Maps) Figure
showing Dengue in the Americas
*Dead
Bird Surveillance West Nile (How to follow virus
spread in the USA)
Arboviral
Encephalitides Yellow
Fever (CDC Site Describes Yellow Fever)
More about Arboviruses
? Maps
of West Nile Spread: USA
April 13
Topic 5 Outline:
The Next Flu Pandemic: Where it will come from, where it goes.
*Flu, an
emerging disease (from the expert Robert G. Webster) Flu
Surveillance figure
The next flu pandemic
(Arising from Bird Flu?) List
of Influenza Epidemics
*Evolution
of Bird Flu in Asia, 2005
Interesting: World Health Organizaton Flu
Site More
about Myxoviridae
?
Bird
Flu in depth from BBC The
Z lineage
Graduate Section Meeting: Video: 2005 ASV VIDEO on Influenza Assembly
April 18
Topic 6 Outline:
Mad Cow Disease and Mad Scientists
*Bovine
Spongioform Encephalopathy (BSE) and other related prion diseases
What is Kuru; old BSE news
A
very nice
USDA site on BSE for public comsumption New
link March '06 Prion Figures
Prion
Mutations
April 20 NO CLASS TODAY !
TOPIC 7 WILL BE COVERED LATER
Topic 7 Outline:
Plagues of Populations: Measles and humans.
*A
"simple" measles outbreak in the unvaccinated
*Global
measles and its importation into the USA Map
of Measles Importation
April 25
Topic 8 Outline:
Modern Plague, Ancient Origin - HIV: What happened?
AIDS Statistics (click
down) New
link April'06: Global
map *The origins of
HIV - the emerging story
*Viral
quasi-species or the "how" of RNA virus evolution
Picture: Sexual orientation and other virus sources in Africa compared
to the World HIV in Africa
Picture:
Epidemic
curve
April 27
Topic 9 Outline:
Rodent Reservoirs: Hemorrhagic Fevers, Hantaviruses, and ?
*What
is a hemorrhagic fever? Arenaviruses
*All about rodent
reservoirs
and Hantavirus Biosafety
Levels
CDC Site on Hantavirus
Hanta
is a global disease
Graduate Section Papers: Influenza
sequencing Bird Flu Lineages
May 2
Topic 10 Outline: What about
Ebloa? And other new viruses that have emerged in 2006?
What are or will be the consequences?
*Risk
factors of Ebola Transmission
Ebola
Hemorrhagic fever info packet Filoviruses
(CDC)
Ebola
Natural History Filoviridae
May 9 Final Exam.
The final exam covers the virus section
of the course and is scheduled for Tuesday, May 9, 2-4.
Click
here for good links to epidemiology and basic microbiology sites:
