Topics
and Outlines
Note: The lecture outlines and required readings will be available for purchase
as CLASS NOTES at the UA Bookstore
Each topic outline below
can be used to follow along with the lecture. The outlines contain the topics,
mostly in order, that are covered in class. In addition, each outline has study
questions and a case history for review.You should be able to answer these
questions and fully understand the case history. The questions and some of the
cases will not be specifically covered in class, but you can bring up the questions
in class if you wish. Available here are the case histories
from all the outlines, all of the questions from
the outlines, and brief answers. In addition,
you may find the study guide questions, drawn from previous exams, very useful.
You are expected to read 1-2 items before the lecture, either
from the on-line version or the printed version, available as a class packet at
the bookstore. Other items listed below are optional (and not included inthe printed
packet) and interesting. If you are curious about the virus that is presented
in class you can learn more about that group of viruses by clicking on the virus
family name. The exam questions will be derived from the lecture and required
reading only.
Final Exam Study Guide Questions
Topic
1 Outline: Emergence,
then Disappearance? SARS (2002-3) and Nipah virus (1998-1999) Slides: HTML | PPT | Handout
Optional
introductory paper................."From Pasteur to Genomics: Challenges
in Infectious Disease"
Required
reading: CDC
Summaries:........... CDC
Information sheet on SARS CDC
Summary sheet on Nipah and Hendra
Required
reading for class discussion:...Severe
Acute Respiratory Syndrome - an emergent Coronavirus
Optional
Information: In
the beginning of SARS, A Quote. Guangdong
Province map
Nipah virus geography - CDC investigation of Bats in Malaysia Malysia
map
Want to learn about Coronaviridae ? Or Paramyxoviridae ?
and..Deadly
Nipah virus - an emergent Paramyxovirus
Topic
2 Outline: Foot
and Mouth: Fast-Moving-Disease
Slides: HTML
| PPT | Handout
Required
Reading
for class discussion: The
Foot and Mouth Epidemic In Great Britain (PDF)
or (HTML)
Optional
Information: BBC
News Page 21 Feb 2001 CNN
Report of FMD in Europe, 2001
Grreat Britain FMD Site Department
of Environment, Food and Rural Affairs, Foot and Mouth Information
Want
to learn more about Picornaviridae
? Picornavirus
Family Tree
Topic 3 Outline: Rabies,
Geography, Raccoons, Vampire Bats, and War Slides: HTML
| PPT
| Handout
Required
Reading for class discussion: The
CDC sites on rabies:
Natural History Epidemiology
The
emergence of Racoon Rabies in Eastern USA
Optional Information: Rabies
Cases in Arizona: 2006 Texas
Oral Rabies Vaccine Program
More
about Rhabdoviridae ?
Topic 4 Outline:
Viruses and Vectors: From the Panama Canal, the Nile,
and Old Tires Slides: HTML
| PPT | PPT2| Handout
Required
Reading for class discussion: Resurgence
of vector-borne diseaes (See parts of article dealing with Arboviruses)
Emergence
of Dengue Dead
Bird Surveillance West Nile
Optional Information: Maps
of West Nile Spread: USA
Arboviral
Encephalitides Yellow
Fever (CDC Sites)
More
about Arboviruses
?
Topic 5 Outline:
The Next Flu Pandemic: Where it will come from, where it goes Slides: HTML
| PPT | Handout
Required
Reading for class discussion:
Flu, an
emerging disease (from the expert Robert G. Webster)
Evolution
of Bird Flu in Asia, 2005
Optional Information: The next flu pandemic
(Arising from Bird Flu?) List
of Influenza Epidemics
The
World Health Organizaton Flu
Site
Bird
Flu in depth from BBC
More
about Myxoviridae
?
Topic 6 Outline: Mad Cow Disease and Mad Scientists Slides: HTML | PPT | Handout
Required
Reading for class discussion: Bovine
Spongioform Encephalopathy (BSE) and other related prion diseases
Optional
Information:What is Kuru;
old BSE news A
very nice
USDA site on BSE for public comsumption
Topic 7 Outline:
Plagues of Populations: Measles and humans Slides: HTML
| PPT | Handout
Required
Reading for class discussion: A
"simple" measles outbreak in the unvaccinated
Global
measles and its importation into the USA
Topic 8 Outline:
Modern Plague, Ancient Origin - HIV: What happened? Slides: HTML |PPT | Handout
Required
Reading for class discussion: The
origins of HIV - the emerging story
Viral
quasi-species or the "how" of RNA virus evolution
Optional
Information: AIDS
Statistics (click down) Global
map HIV in Africa USA
AIDS Epidemic
curve
Topic 9 Outline:
Rodent Reservoirs: Hemorrhagic Fevers, Hantaviruses, and ? Slides: HTML
| PPT | Handout
Required
Reading for class discussion: What
is a hemorrhagic fever? Arenaviruses
All
about rodent
reservoirs
and Hantavirus
Optional
Information: CDC Site on Hantavirus
Hanta
is a global disease Biosafety
Levels
Final
Exam: The final exam covers the
virus section of the course.
It will be held
Click
here for good links to epidemiology and basic microbiology sites:
