Host-Microbial Interactions

Host-Microbial Interactions

Syllabus-Spring 2007

VSC 454/554 | MIC 554 (3)

MW 3:00 -4:15 pm

Rm 129 Veterinary Science/Microbiology

Instructor-Joens

The course is designed to provide a review of bacterial-host interactions with emphasis on virulence determinants of food-borne bacteria and host immunity following bacterial infection. Important issues such as bacterial resistance to host factors, immune modulation, and regulation of the host response to bacterial assault will be discussed. Food-borne bacterial epidemiology will also be discussed.

Approximately every fourth lecture period will include a discussion of the current literature on selected topics. Graduate students will be expected to lead the discussion on these papers. Graduate students will also be expected to write a paper on a selected topic related to the course subject.

Class notes in outline form will be provided on the Web. The instructor is willing to accommodate individuals with special needs if notified prior to attendance. The instructor will conduct the class in accordance with the Code of Academic Integrity as described in the general catalog. Talking to fellow students during an exam is prohibited and will be treated as a violation of the Code of Integrity.

DATE		TOPIC
Jan	10	Discuss Syllabus
“	17	Adherence, Invasion, Toxins
“	22	Food Safety Issues
“	24	Campylobacteriosis
“	29	Campylobacteriosis
“	31	Discussion of Virulence Factors
Feb	5	Salmonellosis
“	7	Salmonellosis
“	12	E. coli O157
“	14	E. coli
“	19	Discussion of Food-Safety Risk Factors
Feb	21	Staphylococcus
“	26	Yersina, Shigella
“	28	Clostridium, Listerois
March	5	Vibrios, Review
“	7	Mid-Term
“	19	Innate Immunity
“	21	Antibody
	26	Cytokines
	28	MHC system
April	2	Antigen Processing
“	4	Antigen Processing Discussion
“	9	Complement
“	11	Mucosal Immunity
“	16	Cell-Mediated Immunity
“	18	Adjuvants
“	23	Gene Therapy
“	25	Vaccines
“	30	Mucosal Immunity Discussion
May	2	Review
“	7	Final

Review articles and recent publications will be supplied to the class.
Class notes will be posted and linked to the lecture date above.

Exam points: 454 Undergraduates (454)

Midterm- 50 pts 100-90=A

Final- 50 ” 89-80=B

Total- 100 pts 79-70=C

69-60=D

60 or less=E

Total Points-554 Graduates (554)

Midterm- 50 pts 125-112=A

Final- 50 “ 112-100=B

Discussion 15 “ 99.5-87.5=C

Paper 10 “

Total 125 pts

Research paper:

Due on May 4, 2007.
Must be typed-5 pages, single space, 12 point font.
Must include title, name and date, recent update on a infectious/immunological problem.
References must be included.

Office hrs:

Open door policy, Joens=VSC/MICRO, Rm 316/318

Absence policy

Absences will affect borderline grades

No Class: MLK Holiday-Jan. 15; Spring Break-March 12-16