Immunology is the study of the body's natural defenses against infectious disease. These pages provide resources for MIC 519/419H, an introductory immunology course for graduate students and honors undergraduate students at the University of Arizona. The goals of MIC 519/419H are to familiarize you with basic knowledge of the immune system and promote continued learning by studying the current immunology research literature and techniques. If you are interested in the regular undergraduate section of this course, see MIC 419.
Dr.
Jan Decker Senior Lecturer, Veterinary Science and Microbiology
Room
235, Vet Sci & Micro Phone: 621-8942 Email: jdecker@u.arizona.edu.
Office Hours: http://microvet.arizona.edu/Courses/MIC419/mic419instructor.html
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ANNOUNCEMENTS Exam 2 now available Dr. Akporiaye's powerpoint. Pink sheets (individual reviews of the proposals) are due in class Tuesday November 27. Bring two copies, one with your name for grading and one without your name to be given to the authoring team. Class time is available on Tuesday November 27 for discussing the pink sheets and revising your proposals, as well as evaluating your team members for participation. Class attendance is required. Graded Midterm exams will be available in class Tuesday November 27. Grades are posted on D2L; please check for accuracy. |
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Date
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Topic
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Reading
Proposal Due Dates |
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T Aug 21
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Schedule, Syllabus
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R Aug 23
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Paper 1 Vesikari, T., et al. 2006. Safety and efficacy of a pentavelent human-bovine (WC3) reassortment Rotavirus vaccine . The New England Journal of Medicine 354: 23-33 (January 5)
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Ch
1; Paper 1
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T Aug 28
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Ch
2
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R Aug 30
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Proposal
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Proposal: Team Organization
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T Sept 4
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Ch 3 |
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R Sept 6
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Paper 2:Maddipatla, S. et al. Augmented antitumor activity against B-cell lymphoma by a combination of monoclonal antibodies targeting TRAIL-R1 and CD20. Clinical Cancer Research 13:4556-4564, August 1, 2007.
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Paper 2
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T Sept 11
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4:30 PM TODAY ONLY Generation of Antigen-Specific B and T Cells - Activity, Case 4
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Ch 4
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R Sept 13
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Proposal |
Proposal: Pathogen and Antigens
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T Sept 18
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Ch 5
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R Sept 20
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Paper 3: Chen, X. et al. Distinct endosomal trafficking requirememnts for presentation of autoantigens and exogenous lipids by human CD1d molecules. J. Immunology (2007) 178: 6181-6190.
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Paper 3
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T Sept 25
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Ch
8
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R Sept 27
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Proposal
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T Oct 2
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Ch 9
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R Oct 4
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Paper 4: Lönard, B. M. et al., Estimation of Human herpesvirus 8 prevalence in high-risk patients by analysis of humoral and cellular immunity. Transplantation 84(1): 40-45 July 15, 2007. See also Toolbox ELISA, Flow Cytometry, Antigen Binding Tetramer MHC Peptide, ELISPOT
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Paper 4 |
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T Oct 9
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Ch 10
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R Oct 11
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Proposal
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Proposal: Immune Responses
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T Oct 16
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Case 9 = MIDTERM EXAM (no class)
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Ch 1-5, 8-10
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R Oct 18
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Proposal in-class session: come with your questions about vacines in gneral and your vaccine in particular.
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Ch 11
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T Oct 23
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Exam 1 due by 3:30 PM in VSM 235 and to turnitin.com
No class |
Paper 5
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R Oct 25
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Proposal
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Proposal: Assessment
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T Oct 30
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Allergy and Hypersensitivity Case 10
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Ch 12
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R Nov 1
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Paper 6: Tsuji, N. M. et al. Interleukin-10-secreting Peyers Patch cells are responsible for active suppression in low-dose oral tolerance. Immunology (2001) 103: 458-464.
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Paper 6
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T Nov 6
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Development of the Immune System and Autoimmunity Case 11
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Ch 7 and 13
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R Nov 8
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Proposal
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Proposal: Assembly and Proofreading
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T Nov 13
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HIV and AIDS: Dr. Ahmad, MBIM
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Ch 11
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R Nov 15
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No class
Proposal(Submit for online posting by Friday 11/16 9AM ) |
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T Nov 20
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Proposal: Study Sections
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Proposal: Peer Review
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R Nov 22
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Thanksgiving
Holiday
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***
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T Nov 27
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Course Evaluation, Peer Evaluations
Proposal Individual Pink Sheets will be exchanged IN CLASS |
Proposal: response to Peer Review
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R Nov 29
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No class
Exam 2 now available |
Ch 14
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T Dec 4
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Tumor Immunology, Dr. Akporiaye |
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T Dec 11
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Exam 2 due in Dr. Decker's office and at turnitin.com |
* Text = Janeway et al. Immunobiology The Immune System in Health and Disease, 6th edition, 2005. Case studies and research paper readings will be assigned by the instructor the week before the date they are discussed.
** All papers accessible through Arizona Health Sciences Library electronic site http://www.ahsl.arizona.edu
Go to the Arizona Health Sciences Library (AHSL) at http://www.ahsl.arizona.edu/
Click on Journals in the top menu bar
Click on N in the Electronic Journals box (for New England Journal of Medicine)
Scroll down to the journal name and click on the link (where there are two choices, choose the top one)
Click on GO
If you are off campus, enter your Cat Card number and click SUBMIT. If you are on campus, you will go directly to the journal.
Drop deadlines: no grade 9/14; with a W 10/12; complete withdrawal, 12/5
Syllabus Tutorials ToolBox
Veterinary Science and Microbiology Home DeckerHome
http://microvet.arizona.edu/Courses/VSC519/vsc519index.html
© 2001 Copying allowed for educational purposes only
Written by Janet M. Decker, PhD jdecker@u.arizona.edu
Last modified December 5, 2007
